An Antifungal Tetranortriterpenoid from Swietenia Macrophylla

Authors

  • Consolacion Y. Ragasa Chemistry Department, De La Salle University, Manila
  • Rosana Daniel Chemistry Department, De La Salle University, Manila
  • John A. Rideout Chemistry Department, Central Queensland University, Rockhampton, Queensland

DOI:

https://doi.org/10.26534/kimika.v14i1.21-25

Keywords:

Swietenia macrophylla, Meliaceae, mahogany, swietenolide, 3, 6-diacetylswietenolide, 3-acetylswietenolide, antifungal

Abstract

The chloroform extract of the matured seeds of Swietenia macroplrylla afforded swietenolide. Its structure was elucidated by extensive 1D and 2D NMR spectroscopy and confmned by acetylation. Swietenolide and its acetylated derivatives were found to inhibit the growth of T. mentagrophytes. Swietenolide was inactive against E. coli, S. aureus and C. albicans.

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How to Cite

Ragasa, C. Y., Daniel, R., & Rideout, J. A. (1998). An Antifungal Tetranortriterpenoid from Swietenia Macrophylla. KIMIKA, 14(1), 21–25. https://doi.org/10.26534/kimika.v14i1.21-25

Issue

Vol. 14 No. 1 (1998)

Section

Research Articles

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