The Complete NMR Assignment of the Alkaloids of Ipomoea muricata (L.) Jacq. Convolvulacaea

Authors

  • Mafel C. Ysrael Department of Biochemistry, Faculty of Pharmacy, University of Santo Tomas, España, Manila
  • Peter G. Waterman Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, Scotland
  • Maribel G. Nonato Department of Chemistry, College of Science, University of Santo Tomas, España, Manila

DOI:

https://doi.org/10.26534/kimika.v16i1.25-30

Keywords:

Alkaloids, NMR spectra, Ipomoea muricata

Abstract

The indolizidine alkaloids from locally grown seeds of Ipomoea muricata were previously isolated and identified. These alkaloids were characterized by lD NMR spectroscopy as ipomine, ipalbidine, ipalbinium, and ipalbine. In the course of looking for other bioactive constituents from the seeds, these alkaloids were reisolated. Group separation of the crude extract of the seeds according to polarity yielded butanol fraction from which ipomine and ipalbidine were isolated. The alkaloids ipalbine and ipalbinium were isolated from the water fraction. The alkaloids ipomine and ipalbidine were purified using gel filtration and normal phase chromatography while ipalbine and ipalbinium were purified by reverse phase chromatography.

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How to Cite

Ysrael, M. C., Waterman, P. G., & Nonato, M. G. (2000). The Complete NMR Assignment of the Alkaloids of Ipomoea muricata (L.) Jacq. Convolvulacaea. KIMIKA, 16(1), 25–30. https://doi.org/10.26534/kimika.v16i1.25-30

Issue

Vol. 16 No. 1 (2000)

Section

Research Articles

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