TY - JOUR AU - Ragasa, Consolacion Y. AU - Alimboyoguen, Agnes B. AU - Rideout, John A. PY - 2010/03/01 Y2 - 2024/03/19 TI - An Antimicrobial Triterpene from Shorea guiso JF - KIMIKA JA - KIMIKA VL - 23 IS - 1 SE - Research Articles DO - 10.26534/kimika.v23i1.50-54 UR - https://kimika.pfcs.org.ph/index.php/kimika/article/view/13 SP - 50-54 AB - The dichloromethane extract of the air-dried leaves of Shorea guiso, a critically endangered Philippine tree, afforded shoreic acid (1) by column chromatography. The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy. Compound 1 exhibited antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5, and 0.4, respectively. It also showed antifungal activity against C. albicans and T. mentagropytes with AI of 0.2 and 0.3, respectively. It was inactive against A. niger. ER -