Palladium-Catalyzed Carbonyl Allylation Reactions Using Tin Chloride: A Mini-Review

Authors

  • Mikael John A. Baltazar Department of Chemistry, School of Science & Engineering, Loyola Schools, Ateneo de Manila University, Quezon City 1108
  • Roy Kristian C. Yanela Department of Chemistry, School of Science & Engineering, Loyola Schools, Ateneo de Manila University, Quezon City 1108
  • Armando Jr. M. Guidote Department of Chemistry, School of Science & Engineering, Loyola Schools, Ateneo de Manila University, Quezon City 1108 https://orcid.org/0000-0002-8323-6400
  • Noriyuki Suzuki Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Tokyo

DOI:

https://doi.org/10.26534/kimika.v29i1.22-40

Keywords:

palladium catalysis, tin chloride reduction, allylic alcohols, organometallic chemistry

Abstract

The treatment of allylic alcohols as synthons of carbanions for carbonyl allylation reactions in the presence of a Pd-SnCl2 system has been one of the most interesting and most useful developments demonstrated by Yoshiro Masuyama and co-workers in the field of organic synthesis. The reaction makes use of palladium as an effective catalyst and tin (II) chloride as a low-valent reducing agent which also effectively transforms the allylic group to a nucleophilic group. The organic, as well as organometallic, chemistry of how the transformations occur and how the metals take part in the reaction is of great interest. These could help allow for better optimization of reagents and solvents, for better control of the extent of reaction or yield of desired product, and for possible applications in other reaction systems. This review will focus primarily on the work of Yoshiro Masuyama and various co-workers on carbonyl allylation reactions making use of a Pd-SnCl2 system or substitutes thereof.

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Published

2018-08-04

Issue

Vol. 29 No. 1 (2018)

Section

Review Articles

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How to Cite

Palladium-Catalyzed Carbonyl Allylation Reactions Using Tin Chloride: A Mini-Review. (2018). KIMIKA, 29(1), 22-40. https://doi.org/10.26534/kimika.v29i1.22-40