An Antimicrobial Triterpene from Shorea guiso

  • Consolacion Y. Ragasa Chemistry Department and Center for Natural Sciences and Ecological Research, De La Salle University, Manila
  • Agnes B. Alimboyoguen Chemistry Department and Center for Natural Sciences and Ecological Research, De La Salle University, Manila
  • John A. Rideout Department of Molecular and Life Sciences, Central Queensland University, Queensland, Queensland
Keywords: Shorea guiso, Dipterocarpoceae, shoreic acid, antibacterial

Abstract

The dichloromethane extract of the air-dried leaves of Shorea guiso, a critically endangered Philippine tree, afforded shoreic acid (1) by column chromatography. The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy. Compound 1 exhibited antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5, and 0.4, respectively. It also showed antifungal activity against C. albicans and T. mentagropytes with AI of 0.2 and 0.3, respectively. It was inactive against A. niger.
Published
2010-03-01
How to Cite
Ragasa, C. Y., Alimboyoguen, A. B., & Rideout, J. A. (2010). An Antimicrobial Triterpene from Shorea guiso. KIMIKA, 23(1), 50-54. https://doi.org/10.26534/kimika.v23i1.50-54
Section
Research Articles