Isolation and purification of some bioactive constituents from a marine sponge Dysidea herbacea

Authors

  • Monita Palma Institute of Chemistry, University of the Philippines, Diliman, Quezon City
  • Florentino C. Sumera Institute of Chemistry, University of the Philippines, Diliman, Quezon City

DOI:

https://doi.org/10.26534/kimika.v11i1.33-38

Keywords:

sponges, Dysidea herbacea, antimicrobial activity, isolation

Abstract

Methanolic extracts of six marine sponges (Spirastrella inconstans, Haliclona sp., Acanthella vulgata, Xestospongia (Petrosia) testudinaria, Clathria fasciculata, and Dysidea herbacea) collected from Matabungkay, Batangas and Guimaras, Iloilo, the Philippines, were examined for antimicrobial activity against S. aureus, B. subtilis, P aeruginosa, E. coli, M. avium, C. albicans and T. mentagrophytes. Of the six extracts five were found to be active at least against one of the pathological microbes tested. The extract from Dysidea herbacea was found to be active against four out of six test microbes.

The marine sponge Dysidea herbacea, collected from Guimaras, Iloilo and found very active against Staphylococus aureus, Bacilus subtilis,Mycobacterium avium and Trichophyton mentagrophytes, was further investigated. From the hexane and dichloromethane extract of the said sponge, three active and HPLC pure compounds were isolated.

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How to Cite

Palma, M., & Sumera, F. C. (1995). Isolation and purification of some bioactive constituents from a marine sponge Dysidea herbacea. KIMIKA, 11(1), 33–38. https://doi.org/10.26534/kimika.v11i1.33-38

Issue

Vol. 11 (1995)

Section

Research Articles

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